Studies on cardiac ingredients of plants. XIII: Chemical modification of gitoxin to cardiotonic compounds without vascular contractile effect

DOI: 10.1248/cpb.45.599

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 599 - 607 (1997)

Update date:2022-08-03

Topics:

Authors:

Nagatsu, Akito

Nakamura, Yukitaka

Takemoto, Kouya

Shibatomi, Kazutaka

Nagai, Shin-Ichi

Ueda, Taisei

Sakakibara, Jinsaku

Hidaka, Hiroyoshi

Fujita, Michiko

Hotta, Yoshihiro

Takeya, Kazumi

Asano, Masahisa

Hashimoto, Toshihiro

Asakawa, Yoshinori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.599

Nitrated gitoxins (4) and bufotoxin homologues with various lengths of alkyl chain at C-3 of the steroid nucleus (10) were prepared from gitoxin (1). The pharmacological activities of the resulting compounds (4 and 10) were evaluated by measurement of inh

Full text of DOI:10.1248/cpb.45.599

NII-Electronic Library Service

Products guided by the article

Product name:hydrogen 14β,16β-O-(4-methoxybenzylidene)card-20(22)-enolide-3β-yl 1,10-decanedicarboxylate

Cas No:190579-38-5

R&D Labs maybe for 190579-38-5

Hangzhou LINGEBA Technology Co., Ltd.

Contact:+0086-571-87389059

Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Shenyang Xingzhenghe Chemical Co., Ltd.

Contact:024-23509232

Address:No. 33, Naner Road, Heping Dist.
NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Contact:86-0951-7815345

Address:North side of Qiyuan Road, west side of Yuanfeng Highway, New Material Park, Ningdong Energy and Chemical Industry Base, Ningxia,China
Xiamen XM-Innovation Chemical Co., Ltd

Contact:+86-592-3216205

Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C
Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park

Relevant to this article

Synthesis of 2,5-disubstituted furans via palladium-catalyzed annulation of alkyl 3-oxo-6-heptynoates

Doi:10.1021/jo962386v
(1997)
Multicomponent Synthesis of Uracil Analogues Promoted by Pd-Catalyzed Carbonylation of α-Chloroketones in the Presence of Isocyanates and Amines

Doi:10.1021/acs.joc.5b01270
(2015)
TCP- and phthalimide-protected n-pentenyl glucosaminide precursors for the synthesis of nodulation factors as illustrated by the total synthesis of nodRf-III (C18:1, MeFuc)

Doi:10.1021/jo962362o
(1997)
Photo-induced intramolecular hydrogen transfer in ortho-nitroaniline: A matrix-isolation infrared spectroscopic and quantum-chemical study

Doi:10.1016/j.molstruc.2012.11.061
(2013)
Cyclometallated complexes of palladium(II) with a C,N,N′ terdentate Schiff base donor ligand. Oxidative addition of an aryl-chlorine bond to palladium(0)

Doi:10.1016/S0022-328X(96)06800-3
(1997)
A Trefoil Macrocycle Synthesized by 3-Fold Benzannulation

Doi:10.1021/acs.orglett.8b03099
(2018)

Article Doi