Asymmetric [4+3] cycloadditions from chiral α-chloro imines

Article abstract of DOI:10.1016/S0040-4039(97)00649-7

The first asymmetric [4+3] cycloadditions of 2-aminoallyl cations derived from chiral α-chloro imines to furan and pyrrole systems are reported. The absolute configuration of the major enantiomer of the bicyclic ketone 4a derived from the cycloadducts has been elucidated, and possible rationales for the observed stereoselectivity are discussed.