[2-ω-phenylalkyl)phenoxy]alkylamines: Synthesis and dual dopamine2 (D2) and 5-hydroxytryptamine2 (5-HT2) receptor antagonistic activities

DOI: 10.1248/cpb.46.639

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 639 - 646 (1998)

Update date:2022-08-03

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Authors:

Tanaka, Naoki

Goto, Riki

Ito, Rie

Hayakawa, Miho

Ogawa, Taketoshi

Fujimoto, Koichi

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Article abstract of DOI:10.1248/cpb.46.639

A series of [2-(ω-phenylalkyl)phenoxy]alkylamines was synthesized and their 5-hydroxytryptamine₂ (5-HT₂) and/or dopamine₂ (D₂) receptor antagonistic activities were examined in vitro. [2-(4- Phenylbutyl)phenoxy]

Full text of DOI:10.1248/cpb.46.639

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