Steroids p. 415 - 421 (1997)
Update date:2022-08-05
Topics: Biological testing Starting Material Purification and characterization Further Modifications
Hellrung, Bernhard
Voigt, Brunhilde
Schmidt, Juergen
Adam, Guenter
We report on the synthesis of the brassinosteroid analogs (22R,23R)- 3β,7β,22,23-tetrahydroxy-stigmast-5-ene (13), (22R,23R)-3β,7α,22,23- tetrahydroxy-stigmast-5-ene (15), and (22R,23R)-3β,22,23-trihydroxy- stigmast-5,7-diene (18) by means of the osmium-catalyzed asymmetric dihydroxylation of intermediate 1, available from stigmasterol. This reaction sequence produced the expected (22S,23S)- and (22R,23R)-triols 6 and 7 as well as the 22,23-diketo derivatives 2 and 3. The phytohormone activity of the new brassinosteroid analogs is discussed.
View MoreShanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.
Contact:+86-21-51320130-801, 816
Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
Ningbo Distant Chemicals Co.,Ltd
Contact:86-574-27862490,27862438
Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Contact:+852-8198 2399
Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
Qingdao Kingway Pharmtech Co., Ltd.
Contact:86-532-87118899
Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China
JiangXi Hong Run Chemical Co., Ltd
Contact:+86-0791-88521351
Address:XingHuo industrial zone in YongXiu county
Doi:10.1016/S0040-4039(00)76658-5
(1994)Doi:10.1021/ol062530r
(2006)Doi:10.1016/S0022-328X(96)06727-7
(1997)Doi:10.1016/S0022-328X(96)06754-X
(1997)Doi:10.1016/j.jfluchem.2004.04.004
(2004)Doi:10.1021/acs.joc.5b00335
(2015)
