Retinoids and related compounds. Part 19. Syntheses of 9E- and 9Z-locked retinoic acid analogues and their transcriptional activities as ligands for retinoic acid receptors and retinoid X receptors

DOI: 10.1039/a606719k

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1405 - 1410 (1997)

Update date:2022-08-03

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Authors:

Katsuta, Yuko

Aoyama, Yukiko

Osone, Hisa

Wada, Akimori

Ito, Masayoshi

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Article abstract of DOI:10.1039/a606719k

Novel retinoic acid (RA) analogues, 9E-locked-RA 3 and 9Z-locked RA 4, have been synthesized in order to prohibit geometrical isomerization at the C(9)-C(10) double bond when these ligands interact with the retinoic acid receptor (RAR) and retinoid X rece

Full text of DOI:10.1039/a606719k

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