Direct synthetic approach to N-substituted 1-amino-2,3-dihydro-1H-imidazole-2-thiones

Article abstract of DOI:10.3987/com-96-7715

In an efficient one-pot procedure, the title compounds (8) were obtained by the reaction of α-halo ketones (1) with potassium thiocyanate and monosubstituted hydrazines (3). The reaction is considered to proceed via the formation of azo-alkenes (5) and th