Bioorganic and Medicinal Chemistry Letters p. 2297 - 2302 (1999)
Update date:2022-08-05
Topics:
Finn, John
Langevine, Charles
Birk, Iwona
Birk, Jeff
Nickerson, Karen
Rodaway, Shirley
Compounds designed to mimic the tryptophan synthase α subunit reactive intermediate were found to be potent inhibitors of the enzyme. These compounds are herbicidal and the herbicidal mode of action was demonstrated to be due to disruption of tryptophan biosynthesis.
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