Rational herbicide design by inhibition of tryptophan biosynthesis

DOI: 10.1016/S0960-894X(99)00340-6

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2297 - 2302 (1999)

Update date:2022-08-05

Topics:

Authors:

Finn, John

Langevine, Charles

Birk, Iwona

Birk, Jeff

Nickerson, Karen

Rodaway, Shirley

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Article abstract of DOI:10.1016/S0960-894X(99)00340-6

Compounds designed to mimic the tryptophan synthase α subunit reactive intermediate were found to be potent inhibitors of the enzyme. These compounds are herbicidal and the herbicidal mode of action was demonstrated to be due to disruption of tryptophan biosynthesis.

Full text of DOI:10.1016/S0960-894X(99)00340-6

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