The novel synthesis of the protease inhibitor (S)-1-chloro-3-[(p-tolylsulfonyl)amino]-7-amino-2-[5,5,6,6-3H]heptanone ([3H]T:CK labeled to high specific activity with tritium

DOI: 10.1002/(SICI)1099-1344(199705)39:5<379::AID-JLCR981>3.0.CO;2-I

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 379 - 386 (1997)

Update date:2022-08-02

Topics:

Authors:

Villani Villani

Heys Heys

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/(SICI)1099-1344(199705)39:5<379::AID-JLCR981>3.0.CO;2-I

The protease inhibitor (S)-1-chloro-3-[(p-tolylsulfonyl)amino][5,5,6,6-³H] heptanone (³H³TLCK) was prepared in an overall 41% radiochemical yield with a specific activity of 1.6 Ci/mmol in a 'one-pot' 3 step sequence begin

Full text of DOI:10.1002/(SICI)1099-1344(199705)39:5<379::AID-JLCR981>3.0.CO;2-I

Products guided by the article

Product name:(S)-6-tert-Butoxycarbonylamino-2-(toluene-4-sulfonylamino)-hex-4-ynoic acid

Cas No:191858-87-4

R&D Labs maybe for 191858-87-4

Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Nanjing Capatue Chemical Co., Ltd

Contact:+86-25-86371192 +86-025-85720158

Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Zhongshan Haihong Medicine Co., Ltd.

Contact:86-0760-86925778 （0）18824993998

Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone
Changsha Huajing Powdery Material Technological Co., Ltd.

Contact:86-731-88879686

Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China

Relevant to this article

Pd-catalyzed nucleophilic alkylation of aliphatic aldehydes with allyl alcohols: Allyl, 2-tetrahydrofuryl, and 2-tetrahydropyranyl ethers as useful C₃, C₄, and C₅ sources

Doi:10.1002/anie.200351182
(2003)
Iron-Catalyzed Intramolecular C(sp²)-N Cyclization of 1-(N-Arylpyrrol-2-yl)ethanone O-Acetyl Oximes toward Pyrrolo[1,2-a]quinoxaline Derivatives

Doi:10.1021/acs.joc.5b00915
(2015)
4-hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: A novel, potent, and selective NR1/2B NMDA receptor antagonist

Doi:10.1021/jm990246i
(1999)
A new synthesis of 2-nitroindoles

Doi:10.1016/S0040-4039(02)00696-2
(2002)
A simple route to 4-substituted-3,4-didehydroprolines, mechanistic probes for the inhibition of prolyl-4-hydroxylase

Doi:10.1016/S0040-4039(97)01182-9
(1997)
Synthesis of l -Kynurenine and Homo- l -Kynurenine via an Aza-Fries Rearrangement

Doi:10.1055/s-0040-1707223
(2020)

Article Doi