
Synlett p. 511 - 512 (1997)
Update date:2022-07-29
Topics:
Hasegawa, Tomoyuki
Yoshida, Koji
Hachiya, Katsutoshi
Miyazaki, Makoto
Tsuruta, Hiroshi
Nambu, Fumio
Ohuchida, Shuichi
Kawamura, Masanori
The 5-hydroxycoumaran derivative 1 possessing imidazole group was synthesized from 2-isopropyl-6-methylphenol with high regioselectivity. The compound 1 was the water-soluble antioxidant with potent bioavailability and showed TXA2 synthase inhibition.
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