Tools for cell signaling: Synthesis of the 3-phosphatase-resistant 1,3,4,5-Ins-P4 mimic, 1D-myo-inositol 1,4,5-trisphosphate 3-phosphorothioate

DOI: 10.1021/jo00088a003

Source and publish data:

Journal of Organic Chemistry p. 2279 - 2281 (1994)

Update date:2022-08-04

Topics:

Authors:

Kozikowski

Fauq Fauq

Wilcox Wilcox

Nahorski

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Article abstract of DOI:10.1021/jo00088a003

The synthesis of 1D-myo-inositol 1,4,5-trisphosphate 3-phosphorothioate, a 3-phosphatase-resistant analogue of 1,3,4,5-InsP₄ is reported, and this compound is shown to elicit ⁴⁵Ca²⁺ release with an EC₅₀ which is

Full text of DOI:10.1021/jo00088a003

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