Novel dithiocarbamate carbapenems with anti-MRSA activity

DOI: 10.1016/S0960-894X(97)00272-2

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1617 - 1622 (1997)

Update date:2022-08-03

Topics:

Authors:

Ohtake, Norikazu

Imamura, Hideaki

Kiyonaga, Hideo

Jona, Hideki

Ogawa, Masayuki

Okada, Shigemitsu

Shimizu, Aya

Moriya, Minoru

Sato, Hiroki

Tominaga, Yushin

Yamada, Koji

Nakano, Masato

Ushijima, Ryosuke

Nakagawa, Susumu

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Article abstract of DOI:10.1016/S0960-894X(97)00272-2

A new series of carbapenems, in which disubstituted- aminothiocarbonylthio moiety, directly attached to the C-2 position, were prepared and evaluated for their antibacterial potency. These analogs showed potent activity against high-level MRSA. Among them

Full text of DOI:10.1016/S0960-894X(97)00272-2

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