Tetrahedron p. 2129 - 2142 (1998)
Update date:2022-08-03
Topics:
Micklefield, Jason
Fettes, Kevin J.
Dinucleotide analogues d(TnsnT) and d(TnsnA), in which the phosphodiester linkage of d(TpT) and d(TpA) is replaced by sulfamide [-NHSO2NH-], have been synthesised. Conformational analysis using 3J vicinal coupling constants shows that this modification results in a shift from a predominantly southern (C2'-endo) to northern (C3'-endo) ribose ring conformation. The effect of temperature and concentration changes on ribose conformation, reveals that the modified dinucleosides have a greater propensity to base stack intramolecularly, and in the case d(TnsnA), self-associate.
View MoreWUHU HUAHAI BIOLOGY ENGINEERING CO LTD
Contact:+86-553-3836920
Address:7/F NO.82 LAODONG ROAD WUHU CHINA
Anqing World Chemical Co., Ltd.
Contact:+86-556-5800026
Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.
Contact:+86-186-02659358
Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
website:http://www.oceanchem-group.com
Contact:86-536-8596048
Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Doi:10.1016/S0960-894X(01)00092-0
(2001)Doi:10.1055/s-1997-5752
(1997)Doi:10.1021/ja01593a068
(1956)Doi:10.1016/S0040-4039(97)01372-5
(1997)Doi:10.1002/chem.201703452
(2017)Doi:10.1021/jo970823f
(1997)