Molecules p. 14022 - 14032 (2015)
Update date:2022-09-26
Topics:
Lee, Dahye
Park, Sunhwa
Yu, Yoseb
Shin, Kye Jung
Seo, Jae Hong
3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity.
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