87. Synthesis and Evaluation of 2-{[(2-Oxo-1H-quinolin-8-yl)oxy]methyl}-Substituted α-Methylidene-γ-butyrolactones

DOI: 10.1002/hlca.19970800413

Source and publish data:

Helvetica Chimica Acta p. 1161 - 1168 (1997)

Update date:2022-08-05

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Authors:

Tzeng, Cherng-Chyi

Chen, Yeh-Long

Wang, Chyi-Jia

Wang, Tai-Chi

Chang, Ya-Ling

Teng, Che-Ming

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Article abstract of DOI:10.1002/hlca.19970800413

O-Alkylation of 8-hydroxy-1H-quinolin-2-one (1) afforded 8-(2-oxopropoxy)-1H-quinolin-2-one (2) which was immediately cyclized to form the tricyclic 2,3-dihydro-3-hydroxy-3-methyl-5H-pyrido[1,2,3-de][1,4]benzoxazine-5-one (3). The Reformatsky-type condens

Full text of DOI:10.1002/hlca.19970800413

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