Bioorganic and Medicinal Chemistry Letters p. 1639 - 1644 (1997)
Update date:2022-09-26
Topics:
Su, Sheng-Hui
Iyer, Rajkumar S.
Aggarwal, Sunil K.
Kalra, Krishan L.
A series of novel labeled phosphoramidites and CPG supports 1a-f with a new non-nucleosidic backbone based upon cyclohexyl-4-amino-1,1-dimethanol have been synthesized. These reagents have been used to label oligonucleotides with biotin and fluorescein at the 5'-, the 3'-, and internal positions.
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