Bioorganic and Medicinal Chemistry Letters p. 1941 - 1944 (1997)
Update date:2022-08-04
Topics:
Wender, Paul A.
Lee, Daesung
Lal, Tapan K.
Horwitz, Susan B.
Rao, Srinivasa
Two new taxol analogs 6 and 10 have been prepared from baccatin III (1) and taxol (7a), respectively. Like taxol, both compounds were found to promote microtubule formation and stabilization, although they were less active than taxol. Both 6 and 10 exhibi
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