Bioorganic and Medicinal Chemistry Letters p. 1927 - 1930 (1997)
Update date:2022-07-29
Topics:
Reitz, Allen B.
McDonnell, Mark E.
Baxter, Ellen W.
Codd, Ellen E.
Wu, Wu-Nan
Several of the key metabolites of mazapertine, a novel antipsychotic agent, were prepared in order to firmly establish their chemical structure and to obtain samples for biological testing. Hydroxymazapertine 3 was synthesized via a multi-step procedure starting from 5-fluoro-2-nitrophenol (8). Alcohol 4 was originally proposed for one of the major metabolites, but the confirmed structure after synthesis was isomer 20.
View MoreZhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd
Contact:+86 411 84674606
Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
website:http://www.greenutra.cn
Contact:0086-411-39553357
Address:No. 7-1-1802, Huizhi Garden,Ocean Square,Dalian, 116033, China
website:http://www.jairadhesales.com
Contact:0091-79-26431096
Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
Shanghai Yuking Water Soluble Material Tech Co., Ltd
Contact:86-21-68286299
Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Ningbo Distant Chemicals Co.,Ltd
Contact:86-574-27862490,27862438
Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Doi:10.1021/om9703898
(1997)Doi:10.1016/S0040-4020(98)00236-1
(1998)Doi:10.1016/j.tet.2005.03.117
(2005)Doi:10.1002/anie.199715041
(1997)Doi:10.1002/ejoc.200700123
(2007)Doi:10.1021/ja9710060
(1997)
