An external chiral ligand controlled enantioselective opening of oxirane and oxetane by organolithiums

Article abstract of DOI:10.1016/S0040-4020(97)00701-1

Enantioselective nucleophilic opening reactions of cyclohexene oxide and 3-phenyloxetane were achieved by the combination of an external chiral ligand and organolithiums in the presence of boran trifluoride to give the corresponding alcohols in up to 47% ee.