On a baker's yeast-mediated approach to verapamil's optically active intermediates

DOI: 10.1016/S0040-4020(97)00667-4

Source and publish data:

Tetrahedron p. 10555 - 10564 (1997)

Update date:2022-08-04

Topics:

Authors:

Brenna, Elisabetta

Caraccia, Nicola

Fogliato, Giovanni

Fronza, Giovanni

Fuganti, Claudio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00667-4

Racemic hydroxylactones 11a and 11b were converted through the key aldehyde intermediate 21 into the C₆-C₄ acid 22, showing all the necessary functionalities for the subsequent transformation into verapamil 1. Baker's yeast reduction

Full text of DOI:10.1016/S0040-4020(97)00667-4

Products guided by the article

Product name:3-(3,4-dimethoxyphenyl)-4,5-dioxo-tetrahydrofuran-3-carboxylic acid ethyl ester

Cas No:195260-30-1

R&D Labs maybe for 195260-30-1

WD Silicone Co., Ltd

Contact:+86-27-87204219, +86-27-87215023

Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Synchem Pharma Co.,Ltd(expird)

Contact:+0086-21-61984905-1

Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China

Relevant to this article

New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

Doi:10.1246/cl.1997.935
(1997)
Self-assembly of a series of metal–organic frameworks with semi-rigid multicarboxylate 3,4-bis(carboxymethoxy)benzoic acid ligands

Doi:10.1016/j.poly.2017.06.039
(2017)
Chloride labilization resulting from nucleophilic addition to cis-Ru(tpy)(CO)₂Cl⁺PF₆^-: Synthesis and characterization of new CO₂-bridged and formate complexes of ruthenium

Doi:10.1021/om970493p
(1997)
Ferrocenophanes with interannular boron-phosphorus bridges: Synthesis, structure, and reactivity toward nitrogen bases

Doi:10.1021/om970484g
(1997)
FPMP-protected α-hydroxyphosphonate diesters for the synthesis of pro- oligonucleotides

Doi:10.1080/07328319708002933
(1997)
EPR spectra of [Cr(CO)₂L(η-C₆Me₆)]⁺ (L = PEt₃, PPh₃, P(OEt)₃, P(OPh)₃): Analysis of line widths and determination of ground state configuration from interpretation of

Doi:10.1021/om970251p
(1997)

Article Doi