New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

DOI: 10.1246/cl.1997.935

Source and publish data:

Chemistry Letters p. 935 - 936 (1997)

Update date:2022-08-04

Topics:

Authors:

Obata, Rika

Sunazuka, Toshiaki

Tian, Zhiming

Tomoda, Hiroshi

Harigaya, Yoshihiro

Omura, Satoshi

Smith III, Amos B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1997.935

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

Full text of DOI:10.1246/cl.1997.935

Products guided by the article

Product name:(4aS,5S,6aR,7R,8S,10aS,10bR)-3-((Z)-2-Hydroxy-2-phenyl-vinyl)-4a,7,10a-trimethyl-1-oxo-5,8-bis-trimethylsilanyloxy-7-trimethylsilanyloxymethyl-4a,5,6,6a,7,8,9,10,10a,10b-decahydro-1H-benzo[f]chromene-2-carboxylic acid methyl ester

Cas No:195527-11-8

R&D Labs maybe for 195527-11-8

Heliosense Biotechnologies, Inc.

website:https://www.heliosense.com/

Contact:+86-592-5667290

Address:Xiamen Torch Hi-tech Zone Venture Weiye Building S506
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China
Rizhao Lanxing Chemical Indusrial Co.,Ltd

Contact:86-633-2616708

Address:NO.15 West road Shenglan, Lanshan district, Rizhao City
Xinjiang Zhongtai Chemical Co., Ltd.

Contact:+86-991-8788172

Address:NO.78 XISHAN RD.URUMQI，CHINA
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA

Relevant to this article

Para-Functionalization of N-Substituted 4-amino[2.2]paracyclophanes by Regioselective Formylation

Doi:10.1002/ejoc.202100288
(2021)
Synthesis and SAR of 4-(1H-benzimidazole-2-carbonyl)piperidines with dual histamine H₁/tachykinin NK₁ receptor antagonist activity

Doi:10.1016/S0960-894X(97)10097-X
(1997)
Synthesis and antimicrobial activity of some new N-substituted-5-arylidene- thiazolidine-2,4-diones

Doi:10.1002/jhet.1726
(2014)
Protease-catalysed synthesis of peptides containing histidine and lysine

Doi:10.1016/S0957-4166(98)00134-7
(1998)
Synthesis and biological evaluation of 3-aryloxyalkyl-6-aryl-7H-s-triazolo[3,4-b][1,3,4]thiadiazines

Doi:10.1016/0223-5234(89)90116-5
(1989)
Bromotriphenylphosphonium salt promoted tandem one-pot cyclization to optically active 2-Aryl-1,3-oxazolines

Doi:10.1002/ejoc.201000162
(2010)

Article Doi