New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

DOI: 10.1246/cl.1997.935

Source and publish data:

Chemistry Letters p. 935 - 936 (1997)

Update date:2022-08-04

Topics:

Authors:

Obata, Rika

Sunazuka, Toshiaki

Tian, Zhiming

Tomoda, Hiroshi

Harigaya, Yoshihiro

Omura, Satoshi

Smith III, Amos B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1997.935

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

Full text of DOI:10.1246/cl.1997.935

Products guided by the article

Product name:(4aS,5S,6aR,7R,8S,10aS,10bR)-3-((Z)-2-Hydroxy-2-phenyl-vinyl)-4a,7,10a-trimethyl-1-oxo-5,8-bis-trimethylsilanyloxy-7-trimethylsilanyloxymethyl-4a,5,6,6a,7,8,9,10,10a,10b-decahydro-1H-benzo[f]chromene-2-carboxylic acid methyl ester

Cas No:195527-11-8

R&D Labs maybe for 195527-11-8

DACHANG OLEOCHEMICALS CO.,LTD.

Contact:0543-2875999

Address:Xingbo 10 Road,EDZ,Boxing Town,Shandong
Shanghai PengMo Biotechnology Co.,Ltd

website:http://www.pengmobio.lookchem.com

Contact:86-13052359378

Address:No.218 Hai Qu Road.Shanghai.China
shijiazhuang shuanglian chemical industry co.,ltd

Contact:0311-82190302

Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
LIANYUNGANG YC FINE CHEMICAL CO., LTD

Contact:+86-518-858 99188

Address:Shangdong Modern Bldg, South Greenpark Road, Lianyungang, Jiangsu Pro. China
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo

Relevant to this article

Para-Functionalization of N-Substituted 4-amino[2.2]paracyclophanes by Regioselective Formylation

Doi:10.1002/ejoc.202100288
(2021)
Synthesis and SAR of 4-(1H-benzimidazole-2-carbonyl)piperidines with dual histamine H₁/tachykinin NK₁ receptor antagonist activity

Doi:10.1016/S0960-894X(97)10097-X
(1997)
Synthesis and antimicrobial activity of some new N-substituted-5-arylidene- thiazolidine-2,4-diones

Doi:10.1002/jhet.1726
(2014)
Protease-catalysed synthesis of peptides containing histidine and lysine

Doi:10.1016/S0957-4166(98)00134-7
(1998)
Synthesis and biological evaluation of 3-aryloxyalkyl-6-aryl-7H-s-triazolo[3,4-b][1,3,4]thiadiazines

Doi:10.1016/0223-5234(89)90116-5
(1989)
Bromotriphenylphosphonium salt promoted tandem one-pot cyclization to optically active 2-Aryl-1,3-oxazolines

Doi:10.1002/ejoc.201000162
(2010)

Article Doi