New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

DOI: 10.1246/cl.1997.935

Source and publish data:

Chemistry Letters p. 935 - 936 (1997)

Update date:2022-08-04

Topics:

Authors:

Obata, Rika

Sunazuka, Toshiaki

Tian, Zhiming

Tomoda, Hiroshi

Harigaya, Yoshihiro

Omura, Satoshi

Smith III, Amos B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1997.935

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

Full text of DOI:10.1246/cl.1997.935

Products guided by the article

Product name:(4aS,5S,6aR,7R,8S,10aS,10bR)-3-((Z)-2-Hydroxy-2-phenyl-vinyl)-4a,7,10a-trimethyl-1-oxo-5,8-bis-trimethylsilanyloxy-7-trimethylsilanyloxymethyl-4a,5,6,6a,7,8,9,10,10a,10b-decahydro-1H-benzo[f]chromene-2-carboxylic acid methyl ester

Cas No:195527-11-8

R&D Labs maybe for 195527-11-8

Xi'an Terra Biochem Co. Ltd.

Contact:0086-29-88315623

Address:S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
SHANDONG AONA CHEMICAL CO.,LTD.

Contact:86-532-85762926

Address:LIUYUAN TOWN, ZAOZHUANG CITY, SHANGDONG PROVINCE.

Relevant to this article

Para-Functionalization of N-Substituted 4-amino[2.2]paracyclophanes by Regioselective Formylation

Doi:10.1002/ejoc.202100288
(2021)
Synthesis and SAR of 4-(1H-benzimidazole-2-carbonyl)piperidines with dual histamine H₁/tachykinin NK₁ receptor antagonist activity

Doi:10.1016/S0960-894X(97)10097-X
(1997)
Synthesis and antimicrobial activity of some new N-substituted-5-arylidene- thiazolidine-2,4-diones

Doi:10.1002/jhet.1726
(2014)
Protease-catalysed synthesis of peptides containing histidine and lysine

Doi:10.1016/S0957-4166(98)00134-7
(1998)
Synthesis and biological evaluation of 3-aryloxyalkyl-6-aryl-7H-s-triazolo[3,4-b][1,3,4]thiadiazines

Doi:10.1016/0223-5234(89)90116-5
(1989)
Bromotriphenylphosphonium salt promoted tandem one-pot cyclization to optically active 2-Aryl-1,3-oxazolines

Doi:10.1002/ejoc.201000162
(2010)

Article Doi