A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity.

DOI: 10.1016/S0960-894X(97)00361-2

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2067 - 2070 (1997)

Update date:2022-08-03

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Authors:

Petitou Petitou

Duchaussoy

Bernat Bernat

Hoffmann

Herbert Herbert

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Article abstract of DOI:10.1016/S0960-894X(97)00361-2

A decasaccharide mimic of the heparan sulfate fragment reported to have high affinity for lipoprotein lipase has been synthesised, and shown to release lipase activity in vivo in the rat.

Full text of DOI:10.1016/S0960-894X(97)00361-2

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