A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity.

DOI: 10.1016/S0960-894X(97)00361-2

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2067 - 2070 (1997)

Update date:2022-08-03

Topics:

Authors:

Petitou Petitou

Duchaussoy

Bernat Bernat

Hoffmann

Herbert Herbert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00361-2

A decasaccharide mimic of the heparan sulfate fragment reported to have high affinity for lipoprotein lipase has been synthesised, and shown to release lipase activity in vivo in the rat.

Full text of DOI:10.1016/S0960-894X(97)00361-2

Products guided by the article

Product name:(2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R)-6-Acetoxy-2-acetoxymethyl-5-benzyloxy-4-methoxy-tetrahydro-pyran-3-yloxy)-5-benzoyloxy-4-methoxy-3-(4-oxo-pentanoyloxy)-tetrahydro-pyran-2-carboxylic acid benzyl ester

Cas No:195306-11-7

R&D Labs maybe for 195306-11-7

Shanghai shibo Chemical Co., Ltd

Contact:+86-021-60753516

Address:688 Qiushi Road, Jinshan High-tech Park, Shanghai, China,201512
Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.

Contact:0086-0576-88551200,88886292 ,88880039

Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China

Relevant to this article

Sulfur-mediated carbohydrate chemistry: Use of ortho-thioquinones and α,α'-dioxothiones

Doi:10.1080/10426509708545538
(1997)
An efficient transformation of ethers to N,N′-disubstituted ureas in a Ritter type reaction

Doi:10.1016/j.tetlet.2012.12.027
(2013)
Nodulisporic acid A, a novel and potent insecticide from a nodulisporium Sp. isolation, structure determination, and chemical transformations

Doi:10.1021/ja971664k
(1997)
Copper immobilized on nano-silica triazine dendrimer (Cu(ii)-TD@nSiO ₂) catalyzed synthesis of symmetrical and unsymmetrical 1,3-diynes under aerobic conditions at ambient temperature

Doi:10.1039/c3ra47184e
(2014)
Asymmetric synthesis of (R)- and (S)-methyl (2-methoxycarbonylcyclopent-2-enyl)acetate and (R)- and (S)-2-(2-hydroxymethyl-cyclopent-2-enyl)ethanol

Doi:10.1016/S0957-4166(97)00340-6
(1997)
Doi:10.1007/BF00902676
(1968)

Article Doi