Synthesis of oligonucleotide derivatives containing pyrene labeled glycerol linkers : Enhanced excimer fluorescence on binding to a complementary DNA sequence

DOI: 10.1016/S0040-4039(97)01358-0

Source and publish data:

Tetrahedron Letters p. 6051 - 6054 (1997)

Update date:2022-08-03

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Authors:

Yamana, Kazushige

Takei, Mizuki

Nakano, Hidehiko

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Article abstract of DOI:10.1016/S0040-4039(97)01358-0

The synthesis of a pyrene labeled glycerol linker for multiple internal labeling of oligonucleotides has been described. The oligonucleotide containing two successively incorporated pyrenyl residues exhibits enhanced excimer fluorescence upon hybridization to the complementary DNA segment.

Full text of DOI:10.1016/S0040-4039(97)01358-0

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