Synlett p. 815 - 817 (1997)
Update date:2022-09-26
Topics:
Schneider, Christoph
A stereoselective synthesis of highly substituted and enantiopure tetrahydropyrans from chiral 7-hydroxy-2-alkenoic imides and esters is described. Depending on the carboxylic acid derivative the base-induced cyclization is kinetically or thermodynamically controlled to deliver either tetrahydropyran stereoisomer selectively.
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Doi:10.1016/j.bmcl.2003.10.057
(2004)Doi:10.3184/030823408X314455
(2008)Doi:10.1055/s-1997-990
(1997)Doi:10.1021/ic970584e
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(1997)