Tetrahedron Letters p. 7839 - 7842 (1997)
Update date:2022-09-26
Topics:
Tanoury, Gerald J.
Senanayake, Chris H.
Hett, Robert
Hong, Yaping
Wald, Stephen A.
The first stereoselective synthesis of cis, syn-hydroxyitraconazole isomers via a tricomponent coupling strategy is described. The isomers are prepared from two chiral subunits and connected via an achiral linker. A highly stereoselective route to the cis,syn-isomers is presented.
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