Pivotal role of (E)-3-carbamoyl-1-propenylboronic acid in the combination of Suzuki-Miyaura coupling and enzyme reactions: Synthesis of (3E,5E)-and (3E,5Z)-6-phenyl-3,5-hexadienoic acid

DOI: 10.1246/cl.1997.797

Source and publish data:

Chemistry Letters p. 797 - 798 (1997)

Update date:2022-08-05

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Authors:

Sugai, Takeshi

Yokoyama, Masahiro

Yamazaki, Takahiro

Ohta, Hiromichi

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Article abstract of DOI:10.1246/cl.1997.797

The first example of the enzyme-catalyzed hydrolysis of a nitrile bearing alkenylboronic acid functionality and its application to the synthesis of dienecarboxylic acids are described. (E)-3-Carbamoyl-1-propenylboronic acid was obtained by an incubation o

Full text of DOI:10.1246/cl.1997.797

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