Derivatives of (R)-2-amino-5-methoxytetralin: Antagonists and Inverse Agonists at the Dopamine D2A Receptor

DOI: 10.1016/S0960-894X(99)00345-5

Source and publish data:

Bioorganic and medicinal chemistry letters p. 2167 - 2172 (1999)

Update date:2022-09-26

Topics:

Authors:

Hoeoek, Berit Backlund

Brege, Cecilia

Linnanen, Tero

Mikaels, Aesa

Malmberg, Aesa

Johansson, Anette M.

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Article abstract of DOI:10.1016/S0960-894X(99)00345-5

A series of N-arylmethyl substituted (R)-5-methoxy-2-(propylamino)tetralins has been prepared and evaluated for affinity and efficacy at dopamine (DA) D_2A receptors. The novel compounds appeared to be antagonists or inverse agonists. (R)-2-<(Be

Full text of DOI:10.1016/S0960-894X(99)00345-5

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