Bioorganic and Medicinal Chemistry Letters p. 2357 - 2362 (1997)
Update date:2022-07-29
Topics:
Haraldson, Chad A.
Karle, Jean M.
Freeman, Sandy G.
Duvadie, Rohit K.
Avery, Mitchell A.
Two tricyclic analogs of artemisinin were designed based on a Comparative Molecular Field Analysis (CoMFA) model, and synthesized for antimalarial testing as part of a program to construct and validate modeling tools for drug design of novel antimlarial agents based on the natural product lead, (+)-artemisinin.
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(1997)
