Novel piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation

DOI: 10.1016/j.bmc.2008.09.059

Source and publish data:

Bioorganic and Medicinal Chemistry p. 9804 - 9816 (2008)

Update date:2022-08-05

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Authors:

Fujiwara, Norio

Nakajima, Takashi

Ueda, Yutaka

Fujita, Hitoshi

Kawakami, Hajime

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Article abstract of DOI:10.1016/j.bmc.2008.09.059

Piperidinylpyrimidine derivatives, previously prepared as inhibitors of TNF-α production, were evaluated for their inhibitory activity against HIV-1 LTR activation. Some of these derivatives inhibited activation of HIV-1 LTR-directed CAT gene expression i

Full text of DOI:10.1016/j.bmc.2008.09.059

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