(+)-2-Methyl-4-carboxyphenylglycine (LY367385) selectively antagonises metbotropic glutamate mGluR1 receptors

DOI: 10.1016/S0960-894X(97)10071-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2777 - 2780 (1997)

Update date:2022-08-03

Topics:

Authors:

Clark, Barry P.

Baker, S. Richard

Goldsworthy, John

Harris, John R.

Kingston, Ann E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)10071-3

The synthesis of three novel 4-carboxyphenylglycine (LY367385) selectively antagoises metabotropic glutamate mGluR1 receptors. Resolution of compound 1 showed that the activity resided in the (+)-isomer LY367385.

Full text of DOI:10.1016/S0960-894X(97)10071-3

Products guided by the article

Product name:N-{[4-(tert-Butyl-diphenyl-silanyloxy)-3-methoxy-2-methyl-phenyl]-cyano-methyl}-acetamide

Cas No:198643-39-9

R&D Labs maybe for 198643-39-9

Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang
Wuhan Biet Co., Ltd

website:http://www.biet.com.cn/

Contact:+86-27-8369 8488

Address:No. 6, Building 21, China Merchants Fanwang, Sixin North Road, Hanyang District, Wuhan City, Hubei Province
Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
Tianjin Realet Chemical Technology Co.,Ltd.

website:http://www.realetchem.com

Contact:+86-022-58788819

Address:shuanggang industrial park
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.

Relevant to this article

Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors

Doi:10.1021/jm9903141
(2000)
Doi:10.1557/mrs2001.127
(1942)
Controlled acidolysis of hexacarbonyltris(μ-alkoxo)dirhenium(I) anions: Facile synthesis of hexacarbonylbis(μ-alkoxo)-[μ-1,1′-bis(diphenylphosphino)ferrocene] dirhenium(I) complexes and nonacarbonyltris(μ-methoxo)(μ₃-methoxo)trirhenium(I)

Doi:10.1021/om970614l
(1998)
Synthesis of 1,2,3,5-Substituted Pyrroles through Palladium-Catalyzed Reaction of Ethyl 2-Acetyl-4-Pentynoate Tosylhydrazone with Aryl Iodides

Doi:10.1055/s-1997-1006
(1997)
A versatile ruthenium catalyst for C-C bond formation by C-H bond activation

Doi:10.1002/anie.200603786
(2006)
Synthesis and pharmacology of 6-methylenedihydrodesoxymorphine.

Doi:10.1021/jm00319a001
(1966)

Article Doi