Bioorganic and Medicinal Chemistry Letters p. 2777 - 2780 (1997)
Update date:2022-08-03
Topics:
Clark, Barry P.
Baker, S. Richard
Goldsworthy, John
Harris, John R.
Kingston, Ann E.
The synthesis of three novel 4-carboxyphenylglycine (LY367385) selectively antagoises metabotropic glutamate mGluR1 receptors. Resolution of compound 1 showed that the activity resided in the (+)-isomer LY367385.
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