Synthesis and properties of conformationally rigid cyclouridylic acids having covalent bonding linkers between the uracil 5-position and the 5′-phosphate group

Article abstract of DOI:10.1080/07328319708006125

Conformationally rigid cyclouridylic acid derivatives 2 and 3 having ethylene and propylene bridges, respectively, between the uracil 5-position and the 5′-phosphate group were synthesized. These intramolecularly cyclized compounds have predominantly the ribose pucker of C3′-endo and the g+ orientation around the C4′-C5′ bond. Copyright

Full text of DOI:10.1080/07328319708006125

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Nucleosides and Nucleotides
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Synthesis and Properties of
Conformationally Rigid Cyclouridylic
Acids Having Covalent Bonding Linkers
Between the Uracil 5-Position and the
5′-Phosphate Group
Kohji Seio a , Osamu Kurasawa a , Takeshi Wada a , Kensaku
Sakamoto b , Shigeyuki Yokoyama b & M. Sekinea a
a Department of Life Science , Tokyo Institute of Technology ,
Nagatsuta, Midoriku, Yokohama, 226, Japan
b Department of Biophysics and Biochemistry , The University of
Tokyo , Hongo, Bunnkyoku, Tokyo, 113, Japan
Published online: 16 Aug 2006.
To cite this article: Kohji Seio , Osamu Kurasawa , Takeshi Wada , Kensaku Sakamoto , Shigeyuki
Yokoyama & M. Sekinea (1997) Synthesis and Properties of Conformationally Rigid Cyclouridylic
Acids Having Covalent Bonding Linkers Between the Uracil 5-Position and the 5′-Phosphate Group,
Nucleosides and Nucleotides, 16:7-9, 1023-1032, DOI: 10.1080/07328319708006125
To link to this article: http://dx.doi.org/10.1080/07328319708006125
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