Inhibition of HIV integrase by novel nucleotides bearing tricyclic bases

DOI: 10.1016/S0960-894X(98)00327-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1887 - 1890 (1998)

Update date:2022-08-04

Topics:

Authors:

Zhang, Jianzhong

Neamati, Nouri

Pommier, Yves

Nair, Vasu

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Article abstract of DOI:10.1016/S0960-894X(98)00327-8

5'-Monophosphates of several novel dideoxynucleosides bearing tricyclic nucleobases were synthesized. Both linear and angular ring-extended analogs of isomeric dideoxyadenosine 5'-monophosphate were discovered to have moderate to good inhibition of the vi

Full text of DOI:10.1016/S0960-894X(98)00327-8

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