Tetrahedron p. 16313 - 16326 (1997)
Update date:2022-08-04
Topics:
Coleman, Robert S.
Carpenter, Andrew J.
The synthesis of the C6-C13 aziridino[1,2a]pyrrolidine core substructure of the antitumor agents azinomycins A (1a) and B (1b) is described. Key synthetic steps included Wadsworth-Horner-Emmons olefination for formation of the C7-C8 double bond, an E-sele
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