Second generation synthesis of the quartromicin spirotetronic acid subunits via a Claisen rearrangement-intramolecular aldol sequence

DOI: 10.1016/S0040-4039(97)10416-6

Source and publish data:

Tetrahedron Letters p. 8785 - 8788 (1997)

Update date:2022-08-03

Topics:

Authors:

Roush, William R.

Barda, David A.

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Article abstract of DOI:10.1016/S0040-4039(97)10416-6

Spirotetronate 4 needed for the assignment of stereochemistry to the quartromicins has been synthesized from 9 and 10 by a route featuring a Claisen rearrangement and intramolecular aldol reaction to establish the stereochemistry of the carbon framework.

Full text of DOI:10.1016/S0040-4039(97)10416-6

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