Synthesis of lysophosphatidylserine with 19:4 acyl group, as a novel sodium-potassium ATPase inhibitor, in relation to DLIS-2, an endogenous digoxin-like substance

Article abstract of DOI:10.1016/S0040-4039(00)94492-7

A lysophosphatidylserine with 19:4 acyl group proposed as a candidat of DLIS-2, an endogenous digoxin-like substance was chemically synthesized. The synthetic compound showed a significant activity of Na⁺,K⁺-ATPase inhibition, which has been accepted as a major indicator activity for the essential hypertension.