Conformationally interlocked amides: Remote asymmetric induction by mechanical transfer of stereochemical information

Article abstract of DOI:10.1016/S0040-4039(97)10443-9

The axial conformation of an aromatic tertiary amide group may be powerfully influenced by an adjacent stereogenic centre. Because the amide axis can also control the formation of new chiral centres, the amide can act as a 'relay centre' for the transmiss