α-Oligodeoxynucleotides containing 5-propynyl analogs of α-deoxyuridine and α-deoxycytidine: Synthesis and base pairing properties

Article abstract of DOI:10.1016/S0040-4020(97)10257-5

From propyne and 5-iodo-α,2-deoxyuridine, obtained by glycosylation, 5-propynyl-α,2'-deoxyuridine was synthesized following the procedure of Hobbs. One part was then transformed through displacement of its C4-triazolo derivative with ammonia into 5-propyn