Total synthesis of a glyoxalase I inhibitor and its precursor, (-)-KD16-U1

DOI: 10.1016/S0040-4039(97)10559-7

Source and publish data:

Tetrahedron Letters p. 401 - 402 (1998)

Update date:2022-08-05

Topics:

Authors:

Tatsuta, Kuniaki

Yasuda, Shohei

Araki, Nobuyuki

Takahashi, Masaaki

Kamiya, Yuko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)10559-7

A glyoxalase I inhibitor and (-)-KD16-U1 have been synthesized from D-ribonic acid γ-lactone through SnCl₄-promoted cyclization of a phenylsulfonyl enol silyl ether and regioselective introduction of a hydroxymethyl group.

Full text of DOI:10.1016/S0040-4039(97)10559-7

Products guided by the article

Product name:(3R,4R,5S)-2-Benzenesulfonylmethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-dimethoxymethyl-tetrahydro-furan-2-ol

Cas No:201991-64-2

R&D Labs maybe for 201991-64-2

Lian Xing Chemical Co.,Ltd.

Contact:0792-8228321

Address:10TH Floor No.121 binjiang Road Xunyang District
shijiazhuang alkay chemicals co..ltd(expird)

Contact:86-311-67692035

Address:2601,juntang building,qiaodong district,shijiazhuang
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China

Relevant to this article

The exhaustive silylation of 5-nitro-pentan-2-one: Novel processes and opportunities

Doi:10.1016/S0040-4020(01)00055-2
(2001)
Rational design of 6-methylsulfonylindoles as selective cyclooxygenase-2 inhibitors

Doi:10.1016/j.bmcl.2004.06.075
(2004)
Design, synthesis, characterization and antimicrobial evaluation of some novel hydrazinecarbothioamide, 4-thiazolidinone and 1,2,4-triazole-3-thione derivatives

Doi:10.1002/jhet.4159
(2021)
P-chiral bis(trialkylphosphine) ligands and their use in highly enantioselective hydrogenation reactions [9]

Doi:10.1021/ja973423i
(1998)
A synthetic approach to N -aryl carbamates via copper-catalyzed Chan-Lam coupling at room temperature

Doi:10.1021/jo502828r
(2015)
Triisopropylsilyl protected hexa-1,5-diyne-3,4-dione: A convenient precursor to 2,3-dialkynyl 1,4-diazabutadienes

Doi:10.1055/s-1998-1559
(1998)

Article Doi