Acyclic nucleoside triphosphate analogs as terminators in biocatalytic DNA replication

DOI: 10.1016/S0960-894X(97)10135-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3013 - 3016 (1997)

Update date:2022-08-03

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Authors:

Martinez, Carlos I.

Ansari, M. Ali

Gibbs, Richard

Burgess, Kevin

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Article abstract of DOI:10.1016/S0960-894X(97)10135-4

The acyclic nucleoside triphosphates 1 and 2 were prepared and tested as substrates for several DNA replicating enzymes; AmpliTaq FS and Taquenase accepted these compounds as substrates leading to chain termination.

Full text of DOI:10.1016/S0960-894X(97)10135-4

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