
Tetrahedron Letters p. 927 - 930 (1998)
Update date:2022-07-29
Topics:
Jeon, Geun Sook
Bentrude, Wesley G.
The photochemical SET rearrangement of nucleoside analog-based phosphites 12 and 13, initiated by the singlet excited state of DCN, affords the corresponding diethyl phosphonates 14 and 15. Deprotection of 15 gives phosphonate 16. Treatment of 14 - 16 with base yields the vinylphosphonates 17-19 as the (E)- and (Z)-diastereomers.
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