Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors

DOI: 10.1016/S0960-894X(98)00006-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 277 - 280 (1998)

Update date:2022-07-29

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Authors:

Bouygues

Medou Medou

Quelever

Chermann

Camplo Camplo

Kraus Kraus

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Article abstract of DOI:10.1016/S0960-894X(98)00006-7

The syntheses consisting of replacement of proline amino acid by a 3-pyrrolidinone ring in Phe-Pro analogues are described. Preliminary anti-HIV studies demonstrated the potential activity of this new class of compounds.

Full text of DOI:10.1016/S0960-894X(98)00006-7

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Product name:(S)-2-Amino-1-(3-hydroxy-pyrrolidin-1-yl)-3-phenyl-propan-1-one

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