Synthesis of a ketorolac model via aromatic carbenoid insertion

DOI: 10.1002/hlca.19980810212

Source and publish data:

Helvetica Chimica Acta p. 317 - 323 (1998)

Update date:2022-08-05

Topics:

Authors:

Mueller, Paul

Polleux, Philippe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/hlca.19980810212

The decomposition of diazo ester 2b with chiral Rh(II) catalysts proceeded via intramolecular aromatic carbenoid insertion to the racemic pyrrole derivative 5b in 72% yield. In contrast, the benzoylated precursor 16 afforded no ketorolac 1b when exposed t

Full text of DOI:10.1002/hlca.19980810212

Products guided by the article

Product name:2-benzoyl-4-phenyl-butyric acid methyl ester

Cas No:204767-34-0

R&D Labs maybe for 204767-34-0

zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
Lanzhou huibang biological chemical technology Co., LTD

Contact:0931-7843964

Address:NO.2011,Yannan Road,Chengguan,
HaiNan Periwinkle Pharmaceutical Co.,Ltd.

website:http://www.cchpharm.com/en/index.html

Contact:020-82208978

Address:Gongye road,Wuzhishan city,HaiNan province
Beijing Green Guardee Technology CO,.LTD

Contact:+86-10-69706062

Address:F2 BLdj,5 No.37 Chaoqian Road
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China

Relevant to this article

Synthesis and antiviral activity of novel acyclic nucleosides: Discovery of a cyclopropyl nucleoside with potent inhibitory activity against herpesviruses

Doi:10.1021/jm9705869
(1998)
Unexpected Dipolarophilic Activity of Diphenylvinylphosphine towards Nitrones

Doi:10.1039/c39890000388
(1989)
The synthesis and structures of tantalum complexes that contain a triamido or a diamidoamine ligand

Doi:10.1016/s0020-1693(97)05869-6
(1998)
Role of aldehydic derivatives in the condensation of phenolic compounds with emphasis on the sensorial properties of fruit-derived foods

Doi:10.1021/jf025503y
(2002)
A novel synthetic method of pyrrolo[2,3-b]indoles and its application to the synthesis of (±)-debromoflustramine B¹

Doi:10.3987/COM-97-7989
(1997)
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.

Doi:10.1021/jm980046r
(1998)

Article Doi