Synthesis and Transformations of Methyl (E)-2-(Acetylamino)-3-cyanoprop-2-enoate und Methyl (E)-2-(Benzoylamino)-3-cyanoprop-2-enoate, Versatile Reagents for the Preparation of Polyfunctional Heterocyclic Systems

DOI: 10.1002/hlca.19980810205

Source and publish data:

Helvetica Chimica Acta p. 231 - 235 (1998)

Update date:2022-07-30

Topics:

Authors:

Pizzioli, Lucija

Ornik, Brina

Svete, Jurij

Stanovnik, Branko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/hlca.19980810205

Methyl (E)-2-(acetylamino)-3-cyanoprop-2-enoate (2a) and its 2-benzoyl analog 2b were prepared from the corresponding methyl (Z)-2-(acylamino)-3-(dimethylamino)propenoates 1. Multifunctional compounds 2 are versatile synthons for preparation of polysubstituted heterocyclic systems such as pyrroles 4, pyrimidines 5 and 6, pyridazines 7, pyrazoles 8, 9, and 11, and isoxazoles 10.

Full text of DOI:10.1002/hlca.19980810205

Products guided by the article

Product name:3H-Pyrazole-3-carboxylicacid,3-(acetylamino)-4-cyano-4,5-dihydro-,methyl

Cas No:204767-46-4

R&D Labs maybe for 204767-46-4

Chengdu Boon Stream Chemical Industry Co.,Ltd.

Contact:+86-28-83156758

Address:No.859,Dongzikou Road,Jinniu District,Chengdu,Sichuan,P.R.China
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District
Yancheng Creator Chemical Co., Ltd

Contact:0086-515-88710008 88710068 88710858 88710868

Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Yantai Derun Liquid Crystal Materials Co. Ltd.

website:http://www.ytderun.com

Contact:86-535-6300169

Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI

Relevant to this article

Rhenium-Catalyzed Arylation–Acyl Cyclization between Enol Lactones and Organomagnesium Halides: Facile Synthesis of Indenones

Doi:10.1002/anie.202103465
(2021)
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ET(B) selectivity

Doi:10.1021/jm990170q
(1999)
Antimicrobial activity of fluorinated 1,2-benzisothiazol-3(2H)-ones and 2,2'-dithiobis(benzamides)

Doi:10.1016/0223-5234(94)90132-5
(1994)
Photochemical Reactions. 145^th Communication. Carbonyl vs. Epoxyketone Photochemistry: Photolysis of 1,2;3,4-Diepoxy-2,6,6-trimethyl-1-cyclohexyl Methyl Ketone

Doi:10.1002/hlca.19850680517
(1985)
Yb(OTf)3-catalyzed intermolecular imino Diels-Alder reaction of 2-azetidinone-tethered aryl imines as azadienes

Doi:10.1080/00397910500522157
(2006)
Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1

Doi:10.1021/jm980405i
(1999)

Article Doi