Tetrahedron Asymmetry p. 321 - 327 (1998)
Update date:2022-08-02
Topics:
Bull, Steven D.
Davies, Stephen G.
Moss, William O.
Practical methodology for the bis-O-methylation of (3S)-isopropyl-piperazine-2,5-dione 4 on a 45 g scale to generate Schollkopf's bis-lactim ether chiral auxiliary (3S)-3,6-dihydro-2,5-dimethoxy-3-isopropyl-pyrazine 1 has been developed. Monomethylated intermediates 5 and 6 are reported for the first time. The gelling effects of 4 in a range of common solvents are also described.
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Doi:10.1021/ja973696d
(1998)Doi:10.3987/COM-97-7990
(1998)Doi:10.1021/op000286s
(2000)Doi:10.1002/ejic.200400784
(2005)Doi:10.1002/(SICI)1099-0690(199804)1998:4<595::AID-EJOC595>3.0.CO;2-7
(1998)Doi:10.1055/s-2003-41059
(2003)