Journal of Heterocyclic Chemistry p. 193 - 199 (1998)
Update date:2022-08-04
Topics:
Abel, Mark D.
Hewgill, Randy T.
Malczyk, Katherine J.
Micetich, Ronald G.
Daneshtalab, Mohsen
The synthesis of a series of azole antifungal compounds which incorporate the aminimide functional moiety is described. The procedure involves the reaction of an epoxide intermediate with 1,1-disubstituted hydrazines to form aminimines which are subsequently treated with acyl chlorides resulting in the desired switterionic aminimides. The aminimides were tested for in vitro antifungal activity and found to be moderately active against Candida and Cryptococcus species, but inactive versus Aspergillus.
View MoreXian Changyue Biological Technology Co., Ltd.
website:https://www.xachangyue.com/
Contact:+86-029-88211911
Address:Keji Road NO.70
Puyang Huicheng Electronic Material Co., Ltd
website:http://huichengchem.weba.testwebsite.cn/index_en.html
Contact:+86-393-8910800
Address:West Section Shengli Road, Puyang457000, China
website:http://www.shengmaochem.com
Contact:86-27-82853423, 82819281
Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
Beijing Cooperate Pharmaceutical Co.,Ltd
website:http://www.cooperate-pharm.com/
Contact:86-01060279497
Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Weifang Arylchem Chemical Co., LTD
Contact:86-536-5217866
Address:Development Zone, Shouguang, Shandong Province
Doi:10.1016/S0040-4020(98)00133-1
(1998)Doi:10.1016/S0022-328X(97)00637-2
(1998)Doi:10.1016/S0968-0896(97)10041-4
(1998)Doi:10.1021/jo972243o
(1998)Doi:10.1016/S0022-1139(02)00127-6
(2002)Doi:10.1002/chem.201203296
(2013)
