Polyester and N-methyl analogues of peptide nucleic acids: Synthesis and hybridization properties

Article abstract of DOI:10.1080/07328319908044625

The synthesis of a set of homo-thymine analogues of peptide nucleic acids containing ester or N-methylamide linkages as well as analogues derived from trans-4-hydroxy-L-proline and their hybrids has been accomplished, and their binding affinity to complementary DNA and RNA strands was evaluated.

Full text of DOI:10.1080/07328319908044625

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Nucleosides and Nucleotides
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Polyester and N-Methyl Analogues of
Peptide Nucleic Acids: Synthesis and
Hybridization Properties
V. A. Efimov a , A. A. Buryakova a , M. V. Choob a & O. G.
Chakhmakhcheva a
a Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry , ul.
Miklukho-Maklaya 16/10, Moscow, 117871, Russia
Published online: 04 Oct 2006.
To cite this article: V. A. Efimov , A. A. Buryakova , M. V. Choob & O. G. Chakhmakhcheva (1999)
Polyester and N-Methyl Analogues of Peptide Nucleic Acids: Synthesis and Hybridization Properties,
Nucleosides and Nucleotides, 18:11-12, 2533-2549, DOI: 10.1080/07328319908044625
To link to this article: http://dx.doi.org/10.1080/07328319908044625
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