Synthesis of 2-substituted furanonaphthoquinones using directed metalation and cross coupling reactions

Article abstract of DOI:10.1080/00397919808003070

A synthetic method for the preparation of C-2 substituted furanonaphthoquinones from ortholithium-benzamide and the 2-furan- carboxaldehyde derivative is described. Four 2-alkyl-furanonaphthoquinones and the 2-phenyl-substituted were prepared via phathalide. This route has been shown to be general application to the synthesis of furanonaphthoquinones.

Full text of DOI:10.1080/00397919808003070

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Synthetic Communications: An
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Organic Chemistry
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Synthesis of 2-Substituted
Furanonaphthoquinones Using
Directed Metalation and Cross
Coupling Reactions
a
Sérgia M. Starling∗ , Délio S. Raslan b & Alaíde B.
de Oliveira a
a Faculdade de Farmácia - Universidade Federal
de Minas Gerais, Av. Olegário Maciel, 2360, Belo
Horizonte, MG, CEP 30180-112
b Departamento de Química- ICEx- Universidade
Federal de Minas Gerais
Version of record first published: 20 Aug 2006.
To cite this article: Sérgia M. Starling∗, Délio S. Raslan & Alaíde B. de Oliveira (1998):
Synthesis of 2-Substituted Furanonaphthoquinones Using Directed Metalation and
Cross Coupling Reactions, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 28:6, 1013-1030
To link to this article: http://dx.doi.org/10.1080/00397919808003070
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