2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

DOI: 10.1021/jm00371a006

Source and publish data:

Journal of Medicinal Chemistry p. 591 - 596 (1984)

Update date:2022-08-04

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Authors:

Nagasawa

Goon Goon

Muldoon Muldoon

Zera Zera

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Article abstract of DOI:10.1021/jm00371a006

A number of 2-alkyl- and 2-aryl-substituted thiazolidine-4(R)-carboxylic acids were evaluated for their protective effect against hepatotoxic deaths produced in mice by LD₉₀ doses of acetaminophen. 2(RS)-Methyl-(1b),2(RS)-n-propyl-, and 2(RS)-n

Full text of DOI:10.1021/jm00371a006

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