Radical reactions leading to substituted pyroglutamates

DOI: 10.1016/S0040-4039(98)00254-8

Source and publish data:

Tetrahedron Letters p. 2815 - 2818 (1998)

Update date:2022-08-05

Topics:

Authors:

Baker, S. Richard

Parsons, Andrew F.

Wilson, Michelle

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Article abstract of DOI:10.1016/S0040-4039(98)00254-8

The Bu₃SnH mediated cyclisation of a serine-derived dehydroalanine was shown to provide an efficient approach to a protected 4-phenylpyroglutamate which was elaborated to 4-phenylglutamic acid in good yield. Cyclisation reactions of this type w

Full text of DOI:10.1016/S0040-4039(98)00254-8

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