Tetrahedron Letters p. 3371 - 3374 (1998)
Update date:2022-08-03
Topics:
Razavi, Hossein
Polt, Robin
The concise enantioselective synthesis of iminolyxitol glycosidase inhibitors starting from benzophenone imines of D-serine and L-alanine esters is very efficient. The reductive-alkenylation of the Schiff bases followed by substrate-directed dihydroxylation and amino dehydration gave the polyhydroxylated pyrrolidines in excellent overall yields (19.6% for 3 → 8. 9.9% for 2 → 13.).
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(1998)Doi:10.1107/S0108270198000304
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(1998)Doi:10.1246/bcsj.71.1477
(1998)Doi:10.1016/j.molstruc.2020.128825
(2020)Doi:10.1016/S0040-4039(98)00750-3
(1998)
