Synthesis of [123I]-8-[4-[2-(5-iodothienyl)]-4-oxobutyl]-3-methyl-1- phenyl-1,3,8-triazaspiro[4.5]decan-4-one: A potential dopamine D2 receptor radioligand for SPECT

DOI: 10.1002/(SICI)1099-1344(199805)41:5<363::AID-JLCR90>3.0.CO;2-B

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 363 - 376 (1998)

Update date:2022-08-03

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Authors:

Waterhouse, Rikki N.

Gotsick, J. Timothy

Kabalka, George W.

Goodman, Mark M.

O'Brien O'Brien

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Article abstract of DOI:10.1002/(SICI)1099-1344(199805)41:5<363::AID-JLCR90>3.0.CO;2-B

[¹²³I]-8-[4-[2-(5-Iodothienyl)]-4-oxobutyl]-3-methyl-1-phenyl-1,3,8- triazaspiro[4.5]-decan-4-one (1) has been synthesized as a potential ligand for dopamine D₂ receptors. This new compound proved to be moderate in lipophilicity (log

Full text of DOI:10.1002/(SICI)1099-1344(199805)41:5<363::AID-JLCR90>3.0.CO;2-B

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